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Moderate evidence

Insomnia & sleep & cannabis

The National Academies found moderate evidence for short-term sleep improvement — but mainly as a secondary benefit in people with chronic pain, MS, or fibromyalgia, not for primary insomnia. Chronic THC use can actually degrade sleep architecture over time.

Sources: NASEM 2017 · CBN sleep trial (2024) · CBN insomnia crossover trial (2026)

Most-studied cannabinoids

THCCBD

Safety & cautions

Tolerance and withdrawal can disrupt sleep. CBN has mixed early trial results and is not an established insomnia treatment.

Clinical research below concerns cannabis or cannabinoids, not evidence that a named cultivar treats a condition.

Help us build this responsibly

This page reflects the cited published clinical evidence, and it is a work in progress. Areto is committed to expanding and refining it as new research emerges — so it can genuinely help medical patients make informed choices. If you are a clinician, researcher, or patient with peer-reviewed sources to add, email us at genetics@areto.tech.

Areto Genetics is an educational cannabis catalog. Nothing here is medical advice, and no strain is proven to treat, cure, or prevent any disease. Cannabis affects people differently and carries real risks. Talk to a qualified healthcare provider before using cannabis for any condition — especially if you are pregnant or breastfeeding, an adolescent, taking other medications, or have a heart, liver, or psychiatric condition.