Santhica 27 Strain

Genetics & Lineage

Parentage not published by the breeder. No single parent pair is established for this catalog entry. Areto does not estimate parents it has no report of.

Academic research: Transcriptome SNP analysis found 'Santhica 27' had the lowest number of polymorphisms (122,033 SNPs) of the three varieties compared. (2026; citation)

Academic research: The monoecious Santhica 27 genome has two alleles each of CsCEN1 and CsFT3, one per X haplotype. (2025; citation)

Effects

Aroma & Taste

Academic research (10 studies)

Peer-reviewed, open-access studies that examined samples sold or grown under this name. Findings describe those samples, not the breeder’s release, and may not match every product. Each quote is copied from the paper’s full text.

• Cannabinoids: Santhica 27 (5 plants) had 0.00% CBD and 0.00% THC, classed as Fiber type.
  Fiber

  “Santhica 27 | 5 | 0.00 | - | 0.00 | - | 0.0 | Fiber”

  Cascini F et al. (2019). Highly Predictive Genetic Markers Distinguish Drug-Type from Fiber-Type Cannabis sativa L. Plants (Basel, Switzerland). doi:10.3390/plants8110496

• Cannabinoids: Santhica 27 had one of the lowest CBD amounts (0.26%) among the genotypes studied.
  CBD 0.26%

  “In Santhica 27, one of the lowest amounts of CBD (0.26%) was detected, followed by Ermo, which showed the lowest CBD content of all studied genotypes”

  Fulvio F et al. (2021). Analysis of Sequence Variability and Transcriptional Profile of Cannabinoid synthase Genes in Cannabis sativa L. Chemotypes with a Focus on Cannabichromenic acid synthase. Plants (Basel, Switzerland). doi:10.3390/plants10091857

• Cannabinoids: Hemp cultivar Santhica 27 lacks both synthase genes (THCAS and CBDAS) and is known to mostly produce CBGA.

  “hemp cultivar Santhica 27, lacking both synthase genes (FSA in Fig. 3A) and known to mostly produce CBGA (48)”

  Ren G et al. (2021). Large-scale whole-genome resequencing unravels the domestication history of Cannabis sativa. Science advances. doi:10.1126/sciadv.abg2286

• Cannabinoids: In an HPLC comparison of hemp varieties, Santhica 27 had the lowest CBD content.

  “The varieties with the highest CBD content were ‘CS’ and ‘Carmagnola’, while the lowest amount of CBD was found in ‘Santhica 27’.”

  Sirangelo TM, Ludlow RA, Spadafora ND. (2022). Multi-Omics Approaches to Study Molecular Mechanisms in Cannabis sativa. Plants (Basel, Switzerland). doi:10.3390/plants11162182

• Cannabinoids: SANTHICA 27 was classified as a hemp, female, Type IV chemotype sample with 1.81% CBG and 0.10% THC.
  CBG 1.81%THC 0.10%Type IV

  “77 | SANTHICA 27 | Hemp | CBG: 1.81% THC: 0.10% | Type IV | Female”

  Boutsika A et al. (2025). Molecular profiling and sex determination of <i>Cannabis sativa</i> germplasm collection: Exploring microsatellite markers and high-resolution melting (HRM) analysis. PeerJ. doi:10.7717/peerj.19770

• Cannabinoids: The paper states, citing a reference, that the hemp variety Santhica 27 contains particularly low THC concentrations.
  low THC

  “The variety Santhica 27 contains particularly low THC concentrations [15]”

  Schwerdtfeger J et al. (2025). Replacing Soybean Meal with Hemp Leaves in a Dairy Cow Diet: Plasma Antioxidative Capacity, Inflammatory Parameters and Milk Constituents. Animals : an open access journal from MDPI. doi:10.3390/ani15101414

• Terpenes: Santhica 27 was grouped in a cluster with an overall low amount of all terpenes.

  “A | Santhica 70, 300, 13/08 (full flowering)Santhica 27, 300, 27/08 (full flowering)Finola, 150, 11/08 (end of flowering) | 268.4 ± 40.4 | 0.9 | Finola only: (E)-ocimene.Overall low amount of all terpene”

  André A et al. (2020). Evolution of the Polyphenol and Terpene Content, Antioxidant Activity and Plant Morphology of Eight Different Fiber-Type Cultivars of Cannabis Sativa L. Cultivated at Three Sowing Densities. Plants (Basel, Switzerland). doi:10.3390/plants9121740

• Terpenes: Myrcene is reported as a major or predominant terpene in Santhica 27.
  myrcene

  “Myrcene has also been reported as a major or predominant terpene in several European hemp cultivars, including Bialobrzeskie, Carmagnola, Ferimon, Futura 75, Santhica 27, Santhica 70, Tiborszallasi and Tygra”

  Stoilkovska Gjorgievska V et al. (2026). From Wild-Growing Plants to Promising Candidates for Hemp Variety Development: Morphological and Phytochemical Characterization of Macedonian Cannabis sativa L. Molecules (Basel, Switzerland). PMC13707986

• Genetic analysis: The monoecious Santhica 27 genome has two alleles each of CsCEN1 and CsFT3, one per X haplotype.

  “Accordingly, two alleles of CsCEN1 and CsFT3 (1 per chromosome X haplotype) were identified in female and monoecious genomes ‘Santhica 27’ and ‘White Widow’, while the genes are hemizygous”

  Dowling CA et al. (2025). FT-like genes in Cannabis and hops: sex specific expression and copy-number variation may explain flowering time variation. BMC genomics. doi:10.1186/s12864-025-11975-2

• Genetic analysis: Transcriptome SNP analysis found 'Santhica 27' had the lowest number of polymorphisms (122,033 SNPs) of the three varieties compared.
  122,033 SNPs

  “In contrast, ‘Santhica 27’ had the lowest number of polymorphisms (122,033 SNPs).”

  Eržen M et al. (2026). Population Structure of Genotypes and Genome-Wide Association Studies of Cannabinoids and Terpenes Synthesis in Hemp (Cannabis sativa L.). Plants (Basel, Switzerland). doi:10.3390/plants15020202

Areto Research estimateNot published by the breeder. Areto Research estimated this with AI-assisted review of the strain’s name, reported parentage and commonly described traits; it is not a source, a lab result or a prediction for any product. Details marked “general guess” have low confidence. Each estimate is replaced as soon as a breeder publishes that detail.

Indica, sativa and hybrid are retail shopping labels, not genetics. Parentage is breeder-reported and not DNA-verified. Use your product’s batch COA for tested potency. How Areto sources this page.